This course introduces the evolving development of an empowering clinical social work practice in healthcare. It is an integral learning of psychosocial assessments, empowerment skills, and evidence-based approaches for working with the Chinese and local population to cope with a range of health challenges. The course covers multi-level methods of holistic care from diagnosis, treatment, rehabilitation to palliative phase. The course emphasized the importance of hands-on experiential learning and sharing of clinical experience. Interactive exercises, live demonstration, video illustration, small group discussions, case studies and readings will be provided to build up the knowledge, skills, sensitivity, collaborative capacity, professional ethics and personal strengths of the students.